产品货号：
Z16580
中文名称：
Glutamate receptor 2/GRIA2抗体
英文名称：
Anti-Glutamate receptor 2/GRIA2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Glutamate receptor 2/GRIA2 Antibody |
| 指标别名 | GluA2;GluR 2;GluR B;GluR K2;GLUR2;GLURB;Glutamate receptor 2;GRIA2;HBGR2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IHC-F,IF,ICC,FCM |
| 基因名称 | GRIA2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human GRIA2 recombinant protein (Position:N25-I360).Human GRIA2 shares 99% amino acid (aa) sequence identity with both mouse and rat GRIA2. |
| 实际分子量 | 99KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Glutamate receptor 2,also known as GLUR2,is a protein that in humans is encoded by the GRIA2 gene.This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA),and function as ligand-activated cation channels.GLUR2's cytogenetic location is 4q32.1.The crystal structures of the GLUR2 ligand-binding core in the apo state and in the presence of the antagonist DNQX,the partial agonist kainate,and the full agonists AMPA and glutamate.GLUR2 plays a major role in depression at synapses in which glutamate remains in the synaptic cleft for prolonged periods of time during normal operation of the synapse.The overexpression of GLUR2 increases dendritic spine size and density in hippocampal neurons,and more remarkably,induces spine formation in GABA-releasing interneurons that normally lack spines. |
| Uniprot ID | P42262 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | glutamate receptor,ionotropic,AMPA 2 |
| 蛋白名全称 | Glutamate receptor 2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry 1:50～400 Immunofluorescence (IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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